All functions |
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Analysis Configuration |
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Analysis parameters |
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Create Annotation |
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Benchmark R6 class |
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Estimate contrasts using Wald Test |
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Base class for all Contrasts classes |
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Compute contrasts with group mean imputation |
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Limma moderated contrasts |
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plot contrasts |
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ContrastsProDA Wrapper to results produced by proDA |
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ROPECA reproducibility-optimization method |
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holds results when contrasts are added. |
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Internal Functions by category |
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LFQData R6 class |
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Decorates LFQData with methods to aggregate protein intensities aggregates intensities |
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LFQDataPlotter ---- Create various visualization of the LFQdata |
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Decorates LFQData with methods to compute statistics of interactions |
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Summarize LFQData |
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converts LFQData object to SummarizedExperiment |
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Decorate LFQData with Methods for transforming Intensities |
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Write LFQData, or provide outputs for writing. |
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Likelihood ratio test |
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compute group mean by LOD |
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R6 class representing modelling result |
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R6 interface class representing modelling result |
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Package Data |
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Build protein models from data |
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Cenerate instances of AnalysisTableAnnotation |
prepare benchmark data |
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make Benchmark |
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Merge contrast results coming from two different model. |
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Aggregates e.g. protein abundances from peptide abundances |
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Aggregates e.g. protein abundances from peptide abundances |
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Convert old proflqua configurations (prolfqua 0.4) to new Analysis configurations prolfqua 0.5 |
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load data from prolfqua |
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simulate protein level data with two groups |
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Simulate data, protein, with config with 2 factros Treatment and Background |
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Simulate data, protein and peptide, with config |
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Simulate data, protein, with config |
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Robustly Squeeze Sample Variances |
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Create custom lmer model |
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compute var sd etc for all factor levels |
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add missing values to x vector based on the values of x |